We support bi-directional sync for email subscription status between HubSpot CRM and Mailmodo i.e., if a contact is marked as unsubscribed in HubSpot the same will be updated in Mailmodo as part of the regular sync. 

Similarly, if a record is marked as unsubscribed at an account level in Mailmodo, the same will be updated in HubSpot. 

Both these operations are performed automatically once the integration is enabled and no separate configuration is required by customers.